What are the considerations for using Sitagliptin in patients with hepatic impairment, and how should dosing be adjusted to ensure safety?
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What are the considerations for using Sitagliptin in patients with hepatic impairment, and how should dosing be adjusted to ensure safety?
Sitagliptin should be used with caution in patients with hepatic impairment. No dose adjustment is necessary for mild hepatic dysfunction, but the drug is not recommended in moderate or severe cases.