How does Sitagliptin prevent weight loss in malnourished diabetics, and what mechanisms contribute to its role in maintaining energy balance?
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Can Sitagliptin effectively reduce fasting plasma glucose levels in severely obese diabetics, and how does it influence insulin sensitivity?
Can Sitagliptin prevent beta-cell apoptosis in early diabetes, and how does it contribute to preserving pancreatic function?
What is Sitagliptin’s role in modulating the interaction between insulin and glucagon, and how does this improve glucose homeostasis?
Can Sitagliptin prevent the decline of insulin sensitivity in type 2 diabetes, and how does it compare to other therapies in preserving metabolic health?
What are the benefits of Sitagliptin in managing gestational diabetes, and how does it ensure glycemic control while minimizing risks for both mother and fetus?
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What are the considerations for using Sitagliptin in patients with hepatic impairment, and how should dosing be adjusted to ensure safety?
How does Sitagliptin affect long-term weight management in diabetics, and what benefits does it offer for maintaining a healthy body weight?
Can Sitagliptin reduce vascular stiffness in diabetic patients, and how does this contribute to better cardiovascular health outcomes?
What precautions should be taken when using Sitagliptin during pregnancy, and what are the potential risks for maternal and fetal health?