How does Sitagliptin improve postprandial blood glucose regulation, and what mechanisms contribute to its effectiveness in managing hyperglycemia after meals?
Sunil JoshiExplorer
How does Sitagliptin improve blood glucose regulation in post-meal hyperglycemia?
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Sitagliptin, a DPP-4 inhibitor, enhances incretin hormones, which increase insulin production and decrease glucagon release post-meal, improving glucose control.
By inhibiting the enzyme DPP-4, Sitagliptin prolongs incretin activity, promoting insulin release and decreasing glucagon to stabilize postprandial glucose levels.