How does Metformin affect skin pigmentation and are there specific changes, such as dark spots or discoloration, that patients may experience during long-term use?
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How does Metformin affect skin pigmentation and are there specific changes, such as dark spots or discoloration, that patients may experience during long-term use?
Metformin can cause vitamin B12 deficiency, which may lead to hyperpigmentation or dark patches on the skin over long-term use.
Metformin may cause skin pigmentation changes, typically presenting as dark patches on the skin, a condition known as acanthosis nigricans, often in skin folds.