How does Metformin manage acanthosis nigricans by targeting insulin resistance? Is it a viable treatment for reducing the severity of skin pigmentation associated with this condition?
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How does Metformin affect skin pigmentation and are there specific changes, such as dark spots or discoloration, that patients may experience during long-term use?
Can Metformin cause skin reactions, such as rashes or itching and what steps should be taken if these symptoms occur?