Are there any significant long-term health risks associated with prolonged Metformin use and how should they be monitored or managed?
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Prolonged metformin use can lead to vitamin B12 deficiency, which may cause anemia. Regular blood tests can monitor levels, allowing for timely supplementation if needed.
1. Long-term use of Metformin may lead to vitamin B12 deficiency, requiring regular monitoring and possible supplementation.
2. Extended Metformin use can cause gastrointestinal issues and, rarely, lactic acidosis; regular liver and kidney function tests are recommended.
3. Prolonged Metformin therapy has been linked to a slight risk of hypoglycemia; patients should monitor their blood sugar levels closely.