How does Metformin influence kidney function and what are the risks for patients with pre-existing renal impairment or other risk factors?
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How does Metformin influence kidney function and what are the risks for patients with pre-existing renal impairment or other risk factors?
Metformin can exacerbate renal impairment by potentially causing lactic acidosis, particularly in patients with existing kidney disease or risk factors like dehydration or sepsis.
Metformin can potentially cause lactic acidosis, particularly in patients with impaired kidney function, because it accumulates when renal clearance decreases. Always monitor kidney function closely.
Metformin is excreted by the kidneys, and its use in patients with renal impairment increases the risk of lactic acidosis, a rare but serious complication.
Patients with kidney issues must use Metformin cautiously, as it’s cleared renally and can accumulate, raising the risk of side effects like lactic acidosis.
In individuals with compromised renal function, Metformin may accumulate, heightening the risk of lactic acidosis, which can be fatal. Kidney function monitoring is essential.