What is the mechanism of action of Sitagliptin as a DPP-4 inhibitor, and how does it improve glycemic control by regulating incretin hormones?
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What is the mechanism of action of Sitagliptin as a DPP-4 inhibitor, and how does it improve glycemic control by regulating incretin hormones?
Sitagliptin inhibits DPP-4, an enzyme that degrades incretin hormones. By preventing this, it increases incretin levels, enhancing insulin release and lowering glucagon, thus improving blood glucose control.