1. Consider renal function as fexofenadine is renally excreted; adjust dosage if necessary. Review other meds to avoid interactions.

2. Monitor for increased sensitivity to fexofenadine in geriatric patients, and evaluate the potential interactions with their current medications.

3. Assess kidney health before prescribing fexofenadine, as its clearance decreases with age. Be cautious of interactions with other drugs the patient is taking.

4. When prescribing fexofenadine, check for contraindications with existing conditions like kidney impairment and review all concurrent medications for interactions.

5. Ensure dosage adjustments for fexofenadine in elderly patients, considering their renal function and possible interactions with polypharmacy.