What precautions should be taken when prescribing Diphenhydramine for patients with chronic sinusitis or nasal polyps requiring long-term therapy?
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What precautions should be taken when prescribing Diphenhydramine for patients with chronic sinusitis or nasal polyps requiring long-term therapy?
1. Monitor for increased sedation and anticholinergic effects. Regularly reassess necessity and dosage.
2. Evaluate for alternative treatments due to potential cognitive impacts and tolerance with prolonged use.
3. Assess the risk of urinary retention and angle-closure glaucoma exacerbation in susceptible individuals.
4. Monitor for dryness of mucous membranes and possible worsening of sinus congestion from anticholinergic effects.