What are the potential renal side effects of cefixime, including nephrotoxicity and how should kidney function be monitored in patients taking cefixime for extended periods?
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What are the potential renal side effects of cefixime, including nephrotoxicity and how should kidney function be monitored in patients taking cefixime for extended periods?
Cefixime can cause interstitial nephritis, a reversible form of kidney injury. Monitoring of kidney function with serum creatinine and urine output is advised for long-term use.
Cefixime may rarely lead to renal impairment including acute renal failure. Patients on prolonged therapy should have regular renal function tests, such as blood urea nitrogen and serum creatinine levels.
In some cases, cefixime could cause nephrotoxicity, typically presenting as interstitial nephritis. Regular kidney function tests (e.g., creatinine clearance) are recommended for those on extended treatment.