What are the potential endocrine effects of corticosteroid therapy, including alterations in adrenal gland function, hormonal imbalances and the risk of adrenal suppression?
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1. Corticosteroid therapy can reduce adrenal cortisol production, leading to adrenal insufficiency and disrupted hormonal balance.
2. Prolonged use of corticosteroids may suppress adrenal gland function, risking adrenal crisis if stopped abruptly.
3. Corticosteroid treatment can cause hormonal imbalances, notably suppressing ACTH, which may lead to adrenal suppression.