What are the potential drug interactions with Rosuvastatin, and how can healthcare providers mitigate risks when prescribing it alongside other medications?
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Rosuvastatin may interact with drugs like warfarin, increasing bleeding risk. Providers should monitor INR levels closely when co-prescribing.
Concomitant use of rosuvastatin and cyclosporine can elevate rosuvastatin levels, risking myopathy. Dose adjustments and regular muscle function tests are advised.
When prescribed with gemfibrozil, rosuvastatin can lead to increased risk of myopathy. Avoiding this combination or opting for an alternative statin is recommended.
Antacids containing aluminum or magnesium can reduce rosuvastatin absorption. Administering rosuvastatin 2 hours before antacids can mitigate this interaction.