What are the potential long-term effects of ranitidine use and how do they compare to other treatments for chronic acid-related conditions?
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Long-term ranitidine use is linked to vitamin B12 deficiency and potential kidney issues. Compared to newer PPIs, it has a higher risk of these problems.
Persistent use of ranitidine may increase the risk of gastrointestinal infections. It’s less effective in healing erosive esophagitis than proton pump inhibitors (PPIs).
Chronic use of ranitidine bears a slight risk of developing NDMA, a potential carcinogen, a risk not seen with antacids or PPIs.