What are the differences between Chlorpheniramine and Diphenhydramine in terms of onset of action, duration, and patient tolerability?
Sahil KapoorExplorer
What are the differences between Chlorpheniramine and other first-generation antihistamines like Diphenhydramine?
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Chlorpheniramine has a quicker onset (15-30 min) and lasts 4-6 hours, with fewer sedative effects. Diphenhydramine takes 20-30 min to act, lasts 4-6 hours, but is more sedating.