What are the primary contraindications for methyldopa use, including pre-existing conditions like liver disease or depression and how should these be assessed before prescribing?
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What are the primary contraindications for methyldopa use, including pre-existing conditions like liver disease or depression and how should these be assessed before prescribing?
1. Methyldopa is contraindicated in active liver disease, depression, and pheochromocytoma; liver function and mental health should be assessed.
2. Avoid methyldopa in patients with liver dysfunction, history of severe depression, or catecholamine-secreting tumors; evaluate liver enzymes and mental status.
3. Do not prescribe methyldopa for patients with acute hepatitis, major depression, or pheochromocytoma; prior testing for liver health and depression is critical.
4. Methyldopa should not be used in individuals with hepatic disorders, depression, or pheochromocytoma; assess liver status and psychological health beforehand.