1. Start low-dose unfractionated heparin or low-molecular-weight heparin once bleeding is controlled, typically within 48 hours of injury.

2. Assess individual bleeding risk vs. thrombosis risk to tailor anticoagulant type and dosing, monitoring closely.

3. Use mechanical prophylaxis (compression devices) until pharmacologic treatment is deemed safe, especially in high-risk patients.

4. Continuously reevaluate the need for anticoagulation based on patient recovery progress and ongoing risk assessments.