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Gaurav Chauhan
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Gaurav ChauhanContributor
Asked: November 26, 20242024-11-26T13:27:16+00:00 2024-11-26T13:27:16+00:00In: Healthcare

Is Enalapril a prodrug?

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Is Enalapril classified as a prodrug, meaning it requires conversion into an active form within the body to exert its therapeutic effects or does it act directly without such a conversion process?

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  1. LifeLinkr
    LifeLinkr Luminary
    2024-11-26T14:18:47+00:00Added an answer on November 26, 2024 at 2:18 pm

    Understanding Enalapril’s Mechanism of Action

    • Prodrug Classification: Yes, Enalapril is classified as a prodrug.
    • Conversion Process: It requires conversion into its active form, Enalaprilat, within the body.
    • Therapeutic Action: Enalaprilat inhibits the enzyme ACE (angiotensin-converting enzyme), which reduces blood pressure.
    • Absorption: After oral administration, Enalapril is absorbed and metabolized in the liver before becoming active.
    • Clinical Effectiveness: This conversion process allows Enalapril to exert its antihypertensive effects effectively over time, managing conditions like hypertension and heart failure.

     

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