Chlorpheniramine should be used cautiously in patients with liver or kidney impairment. Dosage may need to be reduced based on the severity of organ dysfunction.

Patients with liver or kidney issues should consult their doctor before taking Chlorpheniramine, as dosage adjustments are often required.

For those with renal or hepatic impairment, Chlorpheniramine dosages should be adjusted. Lower doses or less frequent dosing is generally recommended.