How is nitrofurantoin metabolized and eliminated from the body and how do factors like renal function affect its pharmacokinetics?
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How is nitrofurantoin metabolized and eliminated from the body and how do factors like renal function affect its pharmacokinetics?
Nitrofurantoin is metabolized by liver enzymes and primarily eliminated via the kidneys. Reduced renal function hampers its clearance, necessitating dosage adjustment.