How is erythromycin metabolized and eliminated from the body and what factors, such as liver function, influence its pharmacokinetics and effectiveness?
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How is erythromycin metabolized and eliminated from the body and what factors, such as liver function, influence its pharmacokinetics and effectiveness?
Erythromycin is metabolized primarily by the liver enzyme CYP3A4. Impaired liver function can slow metabolism and increase drug levels, potentially heightening toxicity.