What are the potential interactions between Valium therapy and medications used to treat rheumatoid arthritis, and how can these interactions affect treatment outcomes?
Gaurav ChauhanContributor
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Valium may increase sedation when taken with rheumatoid arthritis medications like methotrexate, affecting alertness and coordination.
1. Valium may enhance the sedative effects of NSAIDs used in RA, increasing drowsiness and affecting motor skills.
2. Concurrent use with methotrexate may elevate liver enzyme levels, requiring closer monitoring of liver function.
3. Valium can potentiate the gastrointestinal side effects of corticosteroids, increasing the risk of ulcers or bleeding.
4. Combining TNF inhibitors with Valium might suppress the immune system excessively, heightening infection risks.
5. Valium and opioids, often prescribed for RA pain, can lead to increased sedation and respiratory depression.