How does tramadol interact with gabapentinoids in managing neuropathic pain and what precautions are needed for combined therapy?
Himanshu PrajapatiContributor
How does tramadol interact with gabapentinoids in managing neuropathic pain?
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Tramadol and gabapentinoids can enhance pain relief when combined. However, they increase the risk of CNS depression and respiratory failure. Careful monitoring is essential.