How does renal impairment influence Glimepiride dosing and safety? Are there alternative treatments recommended for patients with compromised kidney function?
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How does renal impairment influence Glimepiride dosing and safety? Are there alternative treatments recommended for patients with compromised kidney function?
Renal impairment affects glimepiride elimination, increasing hypoglycemia risk. Dose adjustments or alternative medications like DPP-4 inhibitors might be safer options.
In patients with renal impairment, glimepiride clearance decreases, risking severe hypoglycemia. Alternatives such as linagliptin, which does not require renal dosing, are preferred.