How does penicillin interact with anticoagulants, potentially altering bleeding risk and what precautions should healthcare providers take when prescribing it to patients on blood-thinning medications like warfarin?
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Penicillin can enhance the effects of warfarin by inhibiting the bacterial production of vitamin K, necessary for clotting. Physicians should monitor prothrombin time (PT) and adjust warfarin dosage as needed.