How does nifedipine interact with digoxin and what adjustments or monitoring are required to avoid toxicity or reduced effectiveness of either medication?
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1. Nifedipine may increase digoxin levels, risking toxicity. Monitor digoxin levels and adjust dosage as necessary.
2. When using nifedipine with digoxin, closely monitor serum digoxin levels and watch for signs of overdose; dosage adjustments might be required.