How does Metoprolol affect patients with peripheral vascular disease, and does it exacerbate symptoms like claudication or cold sensitivity?
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How does Metoprolol affect patients with peripheral vascular disease, and does it exacerbate symptoms like claudication or cold sensitivity?
1. Metoprolol may exacerbate symptoms of peripheral vascular disease such as claudication due to its beta-blocking effects which can reduce peripheral circulation.
2. In patients with peripheral vascular disease, Metoprolol can worsen symptoms like claudication and increase cold sensitivity by decreasing blood flow to limbs.