How does metoclopramide work and what are its mechanisms of action in treating nausea, vomiting and other gastrointestinal symptoms?
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How does metoclopramide work and what are its mechanisms of action in treating nausea, vomiting and other gastrointestinal symptoms?
Metoclopramide treats nausea and vomiting by blocking dopamine receptors in the brain’s chemoreceptor trigger zone and enhancing gastric motility by increasing lower esophageal sphincter tone and stimulating antral contractions.