How does Metformin impact systemic inflammation in patients with metabolic syndrome or obesity? Does it reduce levels of pro-inflammatory cytokines?
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Metformin moderates systemic inflammation in patients with metabolic syndrome or obesity by reducing levels of pro-inflammatory cytokines, such as TNF-α and IL-6.
Metformin is known to decrease systemic inflammation in obese patients by lowering pro-inflammatory cytokines, thus helping manage insulin resistance and other metabolic issues.
In obese or metabolically challenged individuals, Metformin effectively reduces systemic inflammation by suppressing the secretion of cytokines like TNF-alpha and interleukin-6.