How does Leuprolide work in the treatment of prostate cancer, and what mechanisms underlie its ability to reduce testosterone levels and slow disease progression?
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How does Leuprolide work in the treatment of prostate cancer, and what mechanisms underlie its ability to reduce testosterone levels and slow disease progression?
Leuprolide, a GnRH agonist, inhibits testosterone production by initially stimulating, then desensitizing pituitary gland receptors, reducing LH and FSH release, thus slowing prostate cancer growth.
Leuprolide, a GnRH agonist, reduces testosterone by inhibiting luteinizing hormone release, slowing prostate cancer progression by starving tumor cells of needed androgens.