How does leuprolide interact with angiogenic factors during follicular development, and what are the implications for ovarian stimulation protocols?
Gaurav ChauhanContributor
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How does leuprolide interact with angiogenic factors during follicular development, and what are the implications for ovarian stimulation protocols?
Leuprolide, a GnRH agonist, downregulates LH and FSH levels, reducing angiogenic factors like VEGF in the ovary. This affects follicular angiogenesis, potentially leading to altered ovarian response in stimulation protocols.