How does Leuprolide administration influence metabolic syndrome in patients, particularly in terms of lipid profiles, insulin sensitivity, and body composition changes?
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Leuprolide can worsen metabolic syndrome by increasing insulin resistance and altering lipid profiles, often raising LDL and total cholesterol levels.
Leuprolide therapy in patients may lead to increased fat mass and reduced insulin sensitivity, potentially exacerbating features of metabolic syndrome.
Administration of Leuprolide may lead to adverse changes in body composition, such as increased adiposity, and negatively impact lipid profiles and glucose metabolism.