How does leuprolide influence adrenal gland activity, and what are the potential consequences for stress hormone regulation during treatment?
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Leuprolide downregulates LH and FSH, which reduces adrenal androgen synthesis, potentially impacting stress hormone levels like cortisol during treatment.
Leuprolide reduces gonadotropin secretion, indirectly affecting adrenal function by altering gonadal steroid feedback. This may disrupt cortisol levels, impacting stress responses.