How does insulin therapy impact cancer risk in type 2 diabetes, and what are the mechanisms behind its potential role in promoting or reducing tumor growth?
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1. Insulin therapy in type 2 diabetes may increase cancer risk by promoting cell growth via the insulin-IGF-1 pathway.
2. Some studies suggest insulin therapy might elevate cancer risk due to its anabolic effects, enhancing cell proliferation and survival.
3. Insulin use can reduce blood sugar levels in diabetic patients, indirectly reducing cancer risk by lowering chronic inflammation associated with high glucose.