How does ibuprofen affect gastrointestinal health, including its potential to cause ulcers, gastritis, or bleeding and what strategies can minimize these risks during treatment?
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Ibuprofen can cause ulcers, gastritis, and GI bleeding by inhibiting prostaglandins that protect the stomach lining. Taking it with food, using the lowest effective dose, and avoiding alcohol can minimize risks.
Ibuprofen’s GI risks include ulcers and bleeding, due to its effect on protective stomach prostaglandins. Co-administering with proton pump inhibitors or misoprostol can reduce these risks.