How does Diphenhydramine compare to Loratadine in terms of onset of action, duration of relief, and sedation effects for managing allergy symptoms?
Sahil KapoorExplorer
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Diphenhydramine acts faster (15-30 mins) but causes more sedation and lasts 4-6 hours. Loratadine is less sedating, takes 1-3 hours to work, and provides 24-hour relief.