Diclofenac may increase the metabolism of certain antiepileptics, reducing their effectiveness. Consult healthcare providers before combining.

Diclofenac interacts with antiepileptics by altering drug levels in the blood, which can affect seizure control. Review with a doctor is essential.

For multiple sclerosis medications, diclofenac can heighten liver enzyme levels, potentially impacting drug efficacy and safety. Monitoring is advised.