How does Clopidogrel compare to Aspirin in secondary stroke prevention, and which patient populations benefit most from each therapy in reducing recurrence risk?
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1. Clopidogrel is better than Aspirin for those with contraindications to aspirin or recurrent stroke on aspirin. It is often favored in patients at higher risk of recurrent stroke.
2. Aspirin is typically used in secondary stroke prevention for its cost-effectiveness and accessibility, benefiting most mild stroke patients, whereas Clopidogrel is preferred for patients with aspirin intolerance.
3. Clopidogrel is preferable in patients with a high risk of cardiac events, while Aspirin is effective for general secondary stroke prevention. Both drugs reduce stroke recurrence but differ in patient-specific tolerance and risk profiles.