How does ciprofloxacin influence the pharmacodynamics of other medications, such as those with a narrow therapeutic index and what interactions need to be monitored closely during combined use?
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Ciprofloxacin can elevate serum concentrations of drugs like warfarin, leading to increased bleeding risk. Close monitoring of INR is essential.
Ciprofloxacin inhibits the metabolism of theophylline, risking toxicity. Regular monitoring of theophylline levels is advised during co-administration.