How does bacterial resistance to cefixime develop and what are the key mechanisms by which bacteria become resistant, reducing the antibiotic’s effectiveness in treating infections?
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How does bacterial resistance to cefixime develop and what are the key mechanisms by which bacteria become resistant, reducing the antibiotic’s effectiveness in treating infections?
Bacterial resistance to cefixime develops mainly through mutations that alter penicillin-binding proteins, efflux pumps that expel the drug, and beta-lactamase production which degrades the antibiotic.