How does azithromycin interact with methotrexate and what precautions are necessary for patients on concurrent therapy?
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How does azithromycin interact with methotrexate and what precautions are necessary for patients on concurrent therapy?
Azithromycin may increase methotrexate toxicity by impairing renal excretion. Patients should be monitored for signs of toxicity, such as renal and liver function tests.