How does Atorvastatin compare to Ezetimibe in managing lipid levels, and are there benefits to combining these two medications?
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How does Atorvastatin compare to Ezetimibe in managing lipid levels, and are there benefits to combining these two medications?
Atorvastatin reduces LDL cholesterol by inhibiting HMG-CoA reductase. Ezetimibe works by decreasing cholesterol absorption in the intestine. Combining both enhances lipid-lowering effects.
Atorvastatin primarily lowers LDL-C by blocking liver enzyme activity, while Ezetimibe targets intestinal cholesterol absorption. Together, they offer a synergistic effect, maximizing lipid reduction.