How does aspirin influence the risk of developing peptic ulcers and what preventive measures, such as co-prescribing PPIs, can mitigate this risk?
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1. Aspirin can damage the stomach’s protective lining, increasing ulcer risk. Co-prescribing PPIs helps prevent these ulcers by reducing stomach acid.
2. By inhibiting cyclooxygenase, aspirin lowers stomach mucous production, which raises ulcer risk. Taking PPIs concurrently can offset this by decreasing acid secretion.