How does amoxicillin interact with antacids and are there specific recommendations for spacing their administration to avoid reduced absorption?
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Amoxicillin absorption may be reduced by antacids because they decrease stomach acidity. It’s recommended to take amoxicillin at least 1 hour before or 2 hours after antacids.
Antacids can impair amoxicillin absorption by increasing gastric pH. Ideally, administer amoxicillin 1-2 hours before or after taking an antacid to avoid interaction.