How do corticosteroids influence the risk of developing adrenal insufficiency and what is the approach to tapering therapy to minimize this risk?
Lakshya KumarExplorer
How do corticosteroids influence the risk of developing adrenal insufficiency?
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Corticosteroids can suppress the hypothalamic-pituitary-adrenal (HPA) axis, risking adrenal insufficiency. Tapering should be gradual, reducing the dose slowly over weeks or months to allow HPA axis recovery.