How do corticosteroids influence the hypothalamic-pituitary-adrenal (HPA) axis and what are the risks of adrenal suppression in patients receiving prolonged therapy?
Lakshya KumarExplorer
How do corticosteroids influence the hypothalamic-pituitary-adrenal (HPA) axis?
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Corticosteroids suppress the HPA axis by reducing CRH and ACTH production, risking adrenal insufficiency during prolonged use.