Does Metformin use contribute to fatigue or general feelings of weakness in patients and what are the potential mechanisms or contributing factors for these symptoms?
Gaurav ChauhanContributor
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Yes, metformin use can cause fatigue, potentially due to its impact on vitamin B12 absorption, leading to anemia which manifests as weakness and tiredness.
1. Metformin may cause fatigue through its impact on blood sugar levels and mitochondrial function, potentially leading to decreased energy production in cells.
2. Fatigue from Metformin could be due to gastrointestinal side effects or vitamin B12 deficiency, which disrupts red blood cell production and energy.