How does Enalapril interact with antifungal medications, and are there specific risks when combining these drugs?
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Enalapril may increase the risk of kidney injury when combined with certain antifungals like amphotericin B, due to enhanced nephrotoxic effects.
Combining enalapril with antifungals such as fluconazole can raise enalapril levels, potentially increasing the risk of its side effects like hyperkalemia.
When enalapril is used with antifungals like ketoconazole, the absorption of enalapril can be reduced, decreasing its efficacy in controlling blood pressure.