Do painkillers affect amlodipine efficacy, and are there specific types of pain relievers that should be avoided to prevent adverse interactions?
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1. Painkillers like NSAIDs can reduce the effectiveness of amlodipine by impairing kidney function and altering blood pressure control.
2. Ibuprofen and similar NSAIDs may lessen amlodipine’s effect on lowering blood pressure; paracetamol is generally considered safer.
3. While most painkillers don’t directly affect amlodipine, NSAIDs can decrease its blood pressure-lowering ability by affecting renal function.