Is penicillin effective in treating bacterial meningitis caused by organisms like Streptococcus pneumoniae and what factors, such as resistance or drug penetration into the cerebrospinal fluid, influence its use?
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Is penicillin effective in treating bacterial meningitis caused by organisms like Streptococcus pneumoniae and what factors, such as resistance or drug penetration into the cerebrospinal fluid, influence its use?
Penicillin was traditionally used to treat bacterial meningitis, including infections caused by S. pneumoniae. However, its usage has declined due to increasing penicillin resistance among pneumococcal strains and concerns about its ability to adequately penetrate the cerebrospinal fluid.